Dental and Medical Problems

Dent Med Probl
Index Copernicus (ICV 2020) – 128.41
MEiN – 70 pts
CiteScore (2021) – 2.0
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ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2015, vol. 52, nr 4, October-December, p. 512–515

doi: 10.17219/dmp/60130

Publication type: clinical case

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

Malignant Transformation of Oral Lichen Planus in Labial Location in a 23-Year-Old Woman – Case Report

Transformacja nowotworowa liszaja płaskiego zlokalizowanego na wardze u 23-letniej kobiety – opis przypadku

Barbara Zawadzka1,B,C,D,F, Alina Pūrienė1,A,B,C,D,E,F, Arūnas Rimkevičius1,A,B,C,D,E,F

1 Institute of Odontology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania


Lichen planus (LP) having a potential for malignant transformation is a rare mucocutaneous disease most frequently observed in middle-aged women than in men. LP is uncommon in young patients and the involvement of a labial site and desquamative gingivitis are also rare. LP mainly affects oral mucosa, and skin involvement is rare. Mucosal lesions are usually multiple and have a bilateral, symmetrical manifestation. Mucosal lesions frequently appear on the tongue, gingiva, and mucobuccal fold. Nearly half of the patients has multiple sites of involvement. Oral biopsy with a histopathological evaluation is necessary to validate the clinical diagnosis of LP. Malignant transformation is uncommon for young patients with a short history of LP and without the presence of other co-morbidities. The aim of the present report was to present a 23-year-old patient with an LP lesion which developed into a squamous cell carcinoma on a facial labial site. Different subject-related pathological, diagnostic and treatment aspects are discussed.

Key words

lichen planus, dysplasia, malignant transformation, young age, lip

Słowa kluczowe

liszaj płaski, dysplazja, transformacja nowotworowa, młody wiek, warga

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