Dental and Medical Problems

Dent Med Probl
Impact Factor (IF 2024) – 3.9
Journal Citation Indicator (JCI 2024) - 1.36
Scopus CiteScore (2024) – 5.0
Index Copernicus Value (ICV 2023) – 181.00
MNiSW – 70 pts
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – bimonthly


 

Download original text (EN)

Dental and Medical Problems

2019, vol. 56, nr 4, October-December, p. 433–436

doi: 10.17219/dmp/110682

Publication type: clinical case

Language: English

License: Creative Commons Attribution 3.0 Unported (CC BY 3.0)

Download citation:

  • BIBTEX (JabRef, Mendeley)
  • RIS (Papers, Reference Manager, RefWorks, Zotero)

Odontogenic keratocyst of the mandible: A case report and literature review

Zębopochodna torbiel rogowaciejąca żuchwy – opis przypadku i przegląd piśmiennictwa

Kamil Polak1,B,C,D,F, Magdalena Jędrusik-Pawłowska1,A,C-,F, Bogna Drozdzowska2,B,C,E,F, Tadeusz Morawiec3,A,B,E,F

1 Department of Maxillofacial Surgery, St. Barbara Provincial Specialist Hospital No. 5, Sosnowiec, Poland

2 Department of Pathology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Poland

3 Division of Dental Surgery, Department of Craniomaxillofacial Surgery and Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Bytom, Poland

Abstract

Based on a literature review, we analyzed the World Health Organization (WHO) classification and the treatment algorithm for the odontogenic keratocyst (OKC), formerly referred to as keratocystic odontogenic tumor (KCOT). The KCOT reclassification from benign odontogenic tumors to odontogenic developmental cysts resulted from the emergence of new evidence regarding their morphogenesis and biological behavior. The authors of the most recent 2017 classification do not provide specific guidelines for OKC. Nevertheless, it has been observed that conservative surgical management is not necessarily associated with recurrences characteristic of neoplastic disease. The aim of this paper was to present the effective management strategy for a local recurrence that developed following conservative OKC enucleation in a 53-year-old patient. The treatment for recurrence consisted of enucleation, marginal osteotomy and augmentation with a cancellous bone graft harvested from a tibial tuberosity. A 6-year observation period (clinical and radiological monitoring) revealed normal bone regeneration and no evidence of recurrence. The algorithm applied in our center for the treatment of OKC/KCOT was compared with the management strategies proposed by other authors.

Key words

odontogenic keratocyst, WHO classification, autogenic bone graft, recurrence

Słowa kluczowe

zębopochodna torbiel rogowaciejąca, klasyfikacja WHO, autogenny przeszczep kości, wznowa

References (12)

  1. Kaczmarzyk T, Stypułkowska J, Tomaszewska R. Update of the WHO classification of odontogenic and maxillofacial bone tumors. J Stomatol. 2017;70(5):484–506.
  2. Soluk-Tekkeşin M, Wright JM. The World Health Organization classification of odontogenic lesions: A summary of the changes of the 2017 (4th) edition. Turk Patoloji Derg. 2018;34(1):1–18.
  3. Stoelinga PJW. Keratocystic odontogenic tumour (KCOT) has again been renamed odontogenic keratocyst (OKC). Int J Oral Maxillofac Surg. 2019;48(3):415–416.
  4. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, eds. WHO Classification of Head and Neck Tumours. Lyon, France: IARC (WHO); 2017:235–236.
  5. Robinson RA, Vincent SD. Tumors and Cysts of the Jaws (AFIP Atlas of Tumor Pathology, Series 4, Number 16). Silver Spring, MD: ARP; 2012:30–32.
  6. Sapp JP, Eversole LR, Wysocki GP. Contemporary Oral and Maxillofacial Pathology. 2nd ed. St. Louis, MO: Mosby; 2004:54–56.
  7. Rahnama M, Orzędała-Koszel U, Jenda D, et al. Keratocystic odontogenic tumour (KCOT) of mandible – case report [in Polish]. Mag Stomatol. 2018;29(3):84–88.
  8. Kaczmarzyk T, Mojsa I, Stypułkowska J. A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. Int J Oral Maxillofac Surg. 2012;41(6):756–767.
  9. Menon S. Keratocystic odontogenic tumours: Etiology, pathogenesis and treatment revisited. J Maxillofac Oral Surg. 2015;14(3):541–547.
  10. Johnson NR, Batstone MD, Savage NW. Management and recurrence of keratocystic odontogenic tumor: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116(4):e271–e276.
  11. Tolstunov L, Treasure T. Surgical treatment algorithm for odontogenic keratocyst: Combined treatment of odontogenic keratocyst and mandibular defect with marsupialization, enucleation, iliac crest bone graft, and dental implants. J Oral Maxillofac Surg. 2008;66(5):1025–1036.
  12. DeGould MD, Goldberg JS. Recurrence of an odontogenic keratocyst in a bone graft. Report of a case. Int J Oral Maxillofac Surg. 1991:20(1):9–11.
© Wroclaw Medical University