Dental and Medical Problems

Dent Med Probl
Index Copernicus (ICV 2021) – 132.50
MEiN – 70 pts
CiteScore (2021) – 2.0
JCI (2021) – 0.5
Average rejection rate (2022) – 79.69%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2019, vol. 56, nr 3, July-September, p. 311–316

doi: 10.17219/dmp/109807

Publication type: clinical case

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

Transformation of a glandular odontogenic cyst into mucoepidermoid carcinoma of the mandible: A case report

Transformacja zębopochodnej torbieli gruczołowej w raka śluzowo-płaskonabłonkowego żuchwy – opis przypadku

Mateusz Dymek1,2,A,B,C,D,E,F, Mariusz Książek3,C,D,E, Bogumił Lewandowski2,A,E,F

1 Collegium Medicum of the University of Rzeszów, Poland

2 Department of Maxillofacial Surgery, Fryderyk Chopin Clinical Voivodeship Hospital No.1 in Rzeszów, Poland

3 Department of Pathology, MedLifeCover, Krosno, Poland

Abstract

The glandular odontogenic cyst (GOC) is a rare pathology of odontogenic origin, which can behave unpredictably. It is problematic in clinical, radiographic and histological diagnostics. Intraosseous mucoepidermoid carcinoma (MEC) is a rare tumor which affects the jaws, typically found in the mandible. This malignancy, which usually originates from the salivary glands, can also be caused by a transformation of the mucous cells found in odontogenic cysts. This article presents a rare case of GOC transforming into MEC of the mandible, which was reported during the treatment of a 52-year-old male patient. The aim of this work was to present some of the therapeutic and clinical difficulties encountered when GOC transforms into mucoepidermoid cancer in the mandible, considering the pathomorphological and histological differentiations. The differentiation between MEC and GOC might be difficult through microscopic examination and requires the cooperation of a clinician – a maxillofacial surgeon – and a histopathologist.

Key words

glandular odontogenic cyst, mucoepidermoid carcinoma, neoplastic transformation

Słowa kluczowe

zębopochodna torbiel gruczołowa, rak śluzowo-płaskonabłonkowy, transformacja nowotworowa

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