Dental and Medical Problems

Dent Med Probl
Index Copernicus (ICV 2020) – 128.41
MEiN – 70 pts
CiteScore (2021) – 2.0
JCI – 0.5
Average rejection rate (2021) – 81.35%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2018, vol. 55, nr 4, October-December, p. 441–445

doi: 10.17219/dmp/99203

Publication type: review article

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

Oral findings in Rett syndrome: An update and review of the literature

Zmiany w jamie ustnej w zespole Retta – przegląd współczesnego piśmiennictwa

Edoardo Bianco1,A,B,C,E,F, Denise Rota1,D,F

1 Department of Surgery and Translational Medicine, University of Milano-Bicocca, Milan, Italy


Rett syndrome is a progressive pediatric neurodevelopmental disorder, predominantly affecting females, characterized by a seemingly normal prenatal and perinatal period, followed by neurodevelopmental stagnation, and then rapid regression.
The purpose of this study was to provide an update of the literature on the oral aspects of Rett syndrome and their possible treatment in patients suffering from this pathology. After an electronic and manual search in MEDLINE (PubMed) and the Cochrane Library, 12 articles were found, for a total of 142 patients affected by Rett syndrome. A high prevalence of bruxism, anterior open bite, ogival palate, sucking habits, and difficulties in maintaining oral hygiene was noted. There were also oral findings related to the pharmacological treatment, which included xerostomia, glossitis, erythema multiforme, gingival hyperplasia, dysphagia, and lingual paralysis. It is important for the dentist to know what problems related to the oral cavity can be encountered in a patient diagnosed with Rett syndrome and what preventive measures can be applied.

Key words

autism, bruxism, Rett syndrome, oral manifestations

Słowa kluczowe

autyzm, bruksizm, zespół Retta, objawy w jamie ustnej

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