Dental and Medical Problems
2018, vol. 55, nr 2, April-June, p. 147–152
doi: 10.17219/dmp/90257
Publication type: original article
Language: English
Download citation:
The reparative capacity of different bioactive dental materials for direct pulp capping
Zdolności reparacyjne bioaktywnych materiałów stosowanych w bezpośrednim pokryciu miazgi
1 Faculty of Dentistry, Al-Azhar University, Cairo, Egypt
2 Department of Operative Dentistry, Al-Azhar University, Cairo, Egypt
3 Department of Oral Biology, Future University in Egypt, New Cairo, Egypt
4 Department of Veterinary Surgery, Cairo University, Egypt
Abstract
Background. Maintaining pulp vitality is a major objective in restorative dentistry. Direct pulp capping (DPC) is considered a way to enhance pulp healing and induce reparative dentin. In the present study, 3 capping materials were used and compared in terms of promoting pulp tissue healing after mechanical exposure.
Objectives. The aim of the study was to evaluate the reparative capacity of Biodentine™ (BD), TheraCal® LC and TotalFill® as DPC materials and to assess dentin bridge formation.
Material and Methods. The experiment required 3 groups (1-week group, 1-month group and 3-months group), each consisting of 24 fresh human premolars extracted for orthodontic reasons. A cavity was prepared on the buccal surface of each tooth and the pulp tissue was penetrated to a depth of approx. 1.0 mm. After exposure, hemostasis was obtained and the pulp-capping agents BD, TheraCal LC and TotalFill were applied. A final restoration with GC Fuji IX GP Fast (GC Corporation, Tokyo, Japan) was applied to each tooth to ensure an adequate coronal seal. Tissue samples were collected at 1 week, 1 month and 3 months. The samples were demineralized, sectioned, stained, and histologically graded.
Results. There was a statistically significant difference between TheraCal LC and both BD and TotalFill in terms of pulpal inflammation during the 3 capping periods, while BD and TotalFill showed comparable results, with no statistically significant difference between their results in the 3 capping periods.
Conclusion. TotalFill a newly developed pulp-capping material, offers results comparable to BD in addition to its advantageous handling properties. Although TheraCal LC contains resin ingredients, given proper curing, it seems to be a successful material for DPC and offers superior handling properties.
Key words
pulp vitality, pulp capping, biactive dental materials
Słowa kluczowe
żywotność miazgi, pokrycie miazgi, bioaktywne materiały stomatologiczne
References (27)
- Aguilar P, Linsuwanont P. Vital pulp therapy in vital permanent teeth with cariously exposed pulp: A systematic review. J Endod. 2011;37:581–587.
- Ji YM, Jeon SH, Park JY, Chung JH, Choung YH, Choung PH. Dental stem cell therapy with calcium hydroxide in dental pulp capping. Tissue Eng Part A. 2010;16:1823–1833.
- Hilton TJ. Keys to clinical success with pulp capping: A review of the literature. Oper Dent. 2009;34:615–625.
- Holland R, de Souza V, Nery MJ, Otoboni Filho JA, Bernabe PF, Dezan E. Reaction of dogs’ teeth to root canal filling with mineral trioxide aggregate or a glass ionomer sealer. J Endod. 1999;25:728–730.
- Dammaschke T, Stratmann U, Wolff P, Sagheri D, Schafer E. Direct pulp capping with mineral trioxide aggregate: An immunohistologic comparison with calcium hydroxide in rodents. J Endod. 2010;36:814–819.
- Wongkornchaowalit N, Lertchirakarn V. Setting time and flowability of accelerated Portland cement mixed with polycarboxylate superplasticizer. J Endod. 2011;37:387–389.
- Malkondu O, Karapinar Kazandag M, Kazazoglu E. A review on Biodentine, a contemporary dentine replacement and repair material. Biomed Res Int. 2014;2014:160951. doi: 10.1155/2014/160951
- Ishizaki NT, Matsumoto K, Kimura Y, Wang X, Yamashita A. Histopathological study of dental pulp tissue capped with enamel matrix derivative. J Endod. 2003;29:176–179.
- Souza LC, Yadlapati M, Dorn SO, Silva R, Letra A. Analysis of radiopacity, pH and cytotoxicity of a new bioceramic material. J Appl Oral Sci. 2015;23:383–389.
- Kang SH, Shin YS, Lee HS, et al. Color changes of teeth after treatment with various mineral trioxide aggregate-based materials: An ex vivo study. J Endod. 2015;41:737–741.
- Liu S, Wang S, Dong Y. Evaluation of a bioceramic as a pulp capping agent in vitro and in vivo. J Endod. 2015;41:652–657.
- White JM, Goodis HE, Marshall SJ, Marshall GW. Sterilization of teeth by gamma radiation. J Dent Res. 1994;73:1560–1567.
- Tecles O, Laurent P, Aubut V, About I. Human tooth culture: A study model for reparative dentinogenesis and direct pulp capping materials biocompatibility. J Biomed Mater Res B Appl Biomater. 2008;85:180–187.
- Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc. 1996;127:1491–1494.
- Parolia A, Kundabala M, Rao NN, et al. A comparative histological analysis of human pulp following direct pulp capping with Propolis, mineral trioxide aggregate and Dycal. Aust Dent J. 2010;55:59–64.
- Suhasini K, Madhusudhana K, Suneelkumar C, Lavanya A, Chandrababu KS, Kumar PD. Clinical performance of Class I nanohybrid composite restorations with resin-modified glass-ionomer liner and flowable composite liner: A randomized clinical trial. J Conserv Dent. 2016;19:510–515.
- Laurent P, Camps J, About I. BiodentineTM induces TGF-beta1 release from human pulp cells and early dental pulp mineralization. Int Endod J. 2012;45:439–448.
- Schmalz G, Galler KM. Biocompatibility of biomaterials: Lessons learned and considerations for the design of novel materials. Dent Mater. 2017;33:382–393.
- Koike T, Polan MA, Izumikawa M, Saito T. Induction of reparative dentin formation on exposed dental pulp by dentin phosphophoryn/collagen composite. Biomed Res Int. 2014;2014:745139. doi: 10.1155/2014/745139
- Saleh R, Nagi S, Ezzat M, Ibrahim MZ. In-vivo assessment of dentin bridge formation after using MTA and experimental propolis paste as direct pulp capping material. Res J Pharm Biol Chem Sci. 2016;7:1244–1250.
- Gerzina TM, Hume WR. Diffusion of monomers from bonding resin-resin composite combinations through dentine in vitro. J Dent. 1996;24:125–128.
- Hume WR, Gerzina TM. Bioavailability of components of resin-based materials which are applied to teeth. Crit Rev Oral Biol Med. 1996;7:172–179.
- Chen L, Suh BI. Cytotoxicity and biocompatibility of resin-free and resin-modified direct pulp capping materials: A state-of-the-art review. Dent Mater J. 2017;36:1–7.
- Jeanneau C, Laurent P, Rombouts C, Giraud T, About I. Light-cured tricalcium silicate toxicity to the dental pulp. J Endod. 2017;43:2074–2080.
- Parirokh M, Torabinejad M, Dummer PMH. Mineral trioxide aggregate and other bioactive endodontic cements: An updated overview. Part I: Vital pulp therapy. Int Endod J. 2018;51:177–205.
- Material Safety Data Sheet. 2018. Brasseler USA® Web site. https://brasselerusadental.com/education-resource/safety-data-sheets/. Accessed March 6, 2017.
- Camilleri J, Laurent P, About I. Hydration of Biodentine, TheraCal® LC, and a prototype tricalcium silicate-based dentin replacement material after pulp capping in entire tooth cultures. J Endod. 2014;40:1846–1854.