Dental and Medical Problems

Dent Med Probl
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ISSN 1644-387X (print)
ISSN 2300-9020 (online)
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Dental and Medical Problems

2017, vol. 54, nr 3, July-September, p. 291–295

doi: 10.17219/dmp/74144

Publication type: clinical case

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

Severe alveolar bone loss and internal root resorption in linear IgA disease and eosinophilic granulomatosis with polyangiitis: A rare case report

Nasilony ubytek kości wyrostka zębodołowego i wewnętrzna resorpcja korzeni zębów w przebiegu linijnej IgA dermatozy oraz eozynofilowej ziarniniakowatości z zapaleniem naczyń – opis rzadkiego przypadku

Phisut Amnuaiphanit1,A,B,C,D,E,F, Sarinthon Pariyawathee1,A,B,C,D,E,F, Kobkan Thongprasom1,A,B,C,D,E,F

1 Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand

Abstract

Linear IgA disease (LAD) is rare and there are only a few cases reported where its lesions were limited to the oral mucosa. Eosinophilic granulomatosis with polyangiitis (EGPA) is also a rare multisystemic disease. Therefore, the occurrence of LAD and EGPA in the same patient is very rare. Here we report the oral manifestations of a case of a 24-year-old female who first presented with idiopathic thrombocytopenic purpura (ITP) and was treated with dapsone, with LAD occurring later. Over the next 6 years, this patient developed hypothyroidism, asthma, eosinophilia, glaucoma, abnormal menstruation, arthritis, glomerulonephritis and respiratory tract involvement. Finally, EGPA was diagnosed by her physicians. This is the first case report of LAD and EGPA that radiographically showed the development of generalized severe alveolar bone loss and internal root resorption of the maxillary right second premolar between the first visit and a 2-year follow-up.

Key words

linear IgA disease, eosinophilic granulomatosis with polyangiitis, alveolar bone loss, internal root resorption,

Słowa kluczowe

linijna IgA dermatoza, ziarniniakowatość eozynofilowa z zapaleniem naczyń, ubytek kości wyrostka zębodołowego, wewnętrzna resorpcja korzeni

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