Dental and Medical Problems

Dent Med Probl
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ISSN 1644-387X (print)
ISSN 2300-9020 (online)
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Dental and Medical Problems

2017, vol. 54, nr 2, April-June, p. 205–208

doi: 10.17219/dmp/70528

Publication type: clinical case

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

Squamous cell carcinoma arising in plaque-like oral lichen planus: A case report

Powstanie raka płaskonabłonkowego w przebiegu płytkopodobnej postaci liszaja płaskiego w jamie ustnej – opis przypadku

Chanwit Prapinjumrune1,A,B,C,D,E,F, Risa Chaisuparat2,D,E,F, Thongprasom Kobkan1,A,B,C,D,E,F

1 Oral Medicine Department, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand

2 Oral Pathology Department, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand

Abstract

Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa that commonly occurs in middle-aged or elderly women. In this paper, we describe a case of a 64-year-old woman who presented with red and white lesions in the oral cavity. Intraoral examination revealed a white plaque and white lines with a mild erythematous area on the right buccal mucosa, however, the left buccal mucosa showed only white striae and a mild erythematous area. Biopsy specimens taken twice from the right buccal mucosa demonstrated OLP characteristics. After 7-years of follow-up, an irregularly shaped ulcer was observed on the plaque lesion of the right buccal mucosa. A biopsy was performed again and the final diagnosis of superficially invasive squamous cell carcinoma was made. OLP is classified as a potentially malignant disorder (PMD) of the oral mucosa. Histopathological examination is mandatory to confirm the diagnosis and to exclude dysplasia and malignancy. Due to the malignant potential of OLP, long-term follow-up is strongly recommended, particularly in elderly patients with plaque-like OLP.

Key words

the elderly, lichen planus, squamous cell carcinoma, potentially malignant disorders

Słowa kluczowe

osoby starsze, liszaj płaski, rak płaskonabłonkowy, zmiany przednowotworowe

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