Dental and Medical Problems

Dent Med Probl
Index Copernicus (ICV 2021) – 132.50
MEiN – 70 pts
CiteScore (2021) – 2.0
JCI (2021) – 0.5
Average rejection rate (2022) – 79.69%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

Download PDF

Dental and Medical Problems

2016, vol. 53, nr 4, October-December, p. 551–558

doi: 10.17219/dmp/63945

Publication type: review article

Language: English

Download citation:

  • BIBTEX (JabRef, Mendeley)
  • RIS (Papers, Reference Manager, RefWorks, Zotero)

Creative Commons BY-NC-ND 3.0 Open Access

Novel Bioceramic Root Repair Materials: Review of the Literature

Nowe materiały bioceramiczne do naprawy korzenia – przegląd piśmiennictwa

Dagna Maria Brzęcka1,A,B,C,D, Tomasz Staniowski1,A,C,E,F

1 Department of Conservative and Pediatric Dentistry, Wroclaw Medical University, Wrocław, Poland

Abstract

Bioceramics are specially designed ceramic materials, which, due to their properties such as biocompatibility, bioactivity and a range of physical features, are applied in a variety of medical and dental procedures. The first bioceramic used with success in dentistry was Mineral Trioxide Aggregate, which then became the “golden standard” in endodontics. MTA, however, despite its wide acknowledgement, has several inconvenient clinical drawbacks. To overcome those obstacles the novel bioceramic materials like Biodentine®, BioAggregate®, Calcium Enriched Mixture and EndoSequence® were introduced to the market. In this paper the characteristics of those materials were described in regards to their impact on composition and its influence on the materials’ features, physical properties such as setting time, radiopacity, compressive and pushout bond strength, sealing ability and biological attributes such as bioactivity and biocompatibility. Based on the available publications those materials have a broad range of possible clinical applications which cover root repair procedures such as root-end filing, open apex management or perforation repair, vital pulp therapy as well as regenerative endodontics. Some of them may also be used as canal sealers. Nonetheless, there is still need for further research to confirm the long-term performance of those novel materials.

Key words

mineral trioxide aggregate, ceramics, Biodentine®, BioAggregate®, EndoSequence® root repair material

Słowa kluczowe

mineralny agregat trójtlenków metali, ceramika, Biodentine®, BioAggregate®, EndoSequence®

References (40)

  1. Camilleri J.: Is mineral trioxide aggregate a bioceramic? Int. J. Dent. Sci. 2016, 18, 13–17.
  2. Camilleri J.: The chemical composition of mineral trioxide aggregate. J. Conserv. Dent. 2008, 11, 141–143.
  3. Guo Y., Du T., Li H., Shen Y., Mobuchon C., Hieawy A., Wang Z., Yang Y., Ma J., Haapasalo M.: Physical properties and hydration behavior of a fast-setting bioceramic endodontic material. BMC Oral Health 2016, doi: 10.1186/s12903-016-0184-1.
  4. Camilleri J., Sorrentino F., Damidot D.: Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine and MTA Angelus. Dent. Mater. 2013, 29, 580–593.
  5. Asgary S., Eghbal M., Parirokh M., Torabzadeh H.: Sealing ability of three commercial mineral trioxide aggregates and an experimental root-end filling material. Iran. Endod. J. 2006, 1, 101–105.
  6. Ghazvivni S., Tabrizi M., Kobarfard F., Baghban A., Asgary S.: Ion release and pH of a new endodontic cement, MTA and Portland cement. Iran. Endod. J. 2009, 4, 74–78.
  7. Tanomaru M., Viapiana R., Guerreiro J.: From MTA to new biomaterials based on calcium silicate. Int. J. Dent. Sci. 2016, 18, 18–22.
  8. Jang Y., Lee B., Koh J., Park Y., Joo N., Chang H., Hwang I., Oh W., Hwang Y.: Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials. Restor. Dent. Endod. 2014, 39, 89–94.
  9. Kaup M., Schafer E., Dammaschke T.: An in vitro study of different material properties of Biodentine compared to ProRoot MTA. Head Face Med. 2015, doi: 10.1186/s13005-015-0074-9.
  10. Butt N., Talwar S., Chaudhry S., Nawal R., Yadav S., Bali A.: Comparison of physical and mechanical properties of mineral trioxide aggregate and Biodentine. Indian J. Dent. Res. 2014, 25, 692–697.
  11. Ahmetoglu F., Simsek N., Keles A., Sinan M. Ocak, Altun O.: Radiopacity evaluation of three calcium silicatebased materials by digital radiography. Clin. Dent. Res. 2013, 37, 32–37.
  12. Torabzadeh H., Aslanzadeh S., Asgary S.: Radiopacity of various dental biomaterials. Res. J. Biol. Sci. 2012, 7, 152–158.
  13. Shahi S., Ghasemi N., Rahimi S., Yavari H., Samiei M., Janani M., Bahari M., Moheb S.: The effect of different mixing methods on the flow rate and compressive strength of mineral trioxide aggregate and calcium-enriched mixture. Iran. Endod. J. 2015, 10, 55–58.
  14. Alsubait S., Hashem Q., Alharhan N., Almohimeed K., Alkahtani A.: Comparative evaluation of push-out bond strength of ProRoot MTA, BioAggregate and Biodentine. J. Contemp. Dent. Pract. 2014, 15, 336–340.
  15. Adi A., Sobhnamayan F., Kazemi O.: Comparison of push-out bond strength of mineral trioxide aggregate and calcium enriched mixture cement as root end filling materials. Dent. Res. J. 2014, 11, 564–567.
  16. Shokouhinejad N., Razmi H., Nekoofar M., Sajadi S., Dummer P., Khoshkhounejad M.: Push-out bond strength of bioceramic materials in a synthetic tissue fluid. J. Dent. (Tehran) 2013, 10, 540–547.
  17. Shokouhinejad N., Yazdi K., Nakoofar M., Matmir S., Khoshkhounejad M.: Effect of acidic environment on dislocation resistance of EndoSequence root repair material and mineral trioxide aggregate. J. Dent. (Tehran) 2014, 11, 161–166.
  18. Bolhari B., Yazdi K., Sharifi F., Pirmoazen S.: Comparative scanning electron microscopic study of the marginal adaptation of four root-end filling materials in presence and absence of blood. J. Dent. (Tehran) 2015, 12, 226–234.
  19. Shokouhinejad N., Nekoofar M., Ashoftehyazdi K., Zahraee S., Koshkhounejad M.: Marginal adaptation of new bioceramic materials and mineral trioxide aggregate: A scanning electron microscopy study. Iran Endod. J. 2014, 9, 144–148.
  20. Bani M., Sungurtekin E.-Ekci, Odabas M.: Efficacy of Biodentine as an apical plug in nonvital permanent teeth with open apices: An in vitro study. Biomed. Res. Int. 2015, doi: 10.1155/2015/359275.
  21. Jeevani E., Jayaprakash T., Bolla N., Vemuri S., Sunil C., Kalluru R.: Evaluation of sealing ability of MM-MTA, EndoSequence, and Biodentine as furcation repair materials: UV spectrophotometric analysis. J. Conserv. Dent. 2014, 17, 340–343.
  22. Mirhadi H., Moazzami F., Jahromi S., Safarzade S.: The effects of alkaline pH on microleakage of mineral trioxide aggregate and calcium enriched mixture apical plugs. J. Dent. (Shiraz) 2016, 17, 16–20.
  23. Bayram H., Saklar F., Bayram E., Orucoglu H., Bozkurt A.: Determination of the apical sealing abilities of mineral trioxide aggregate, Portland cement and BioAggregate after irrigation with different solutions. J. Int. Oral Health, 2015, 7, 13–17.
  24. Sayed E., Saeed M.: In vitro comparative study of sealing ability of Diadent BioAggregate and other root-end filling materials. J. Conserv. Dent. 2012, 15, 249–252.
  25. Shokouhinejad N., Nekoofar M., Razmi H., Sajadi S., Davies T., Saghiri M., Gorjestani H., Dummer P.: Bioactivity of EndoSequence Root Repair material and BioAggregate. Int. Endod. J. 2012, 45, 1127–1134.
  26. Atmeh A., Chong E., Richard G., Festy F., Watson T.: Dentin-cement interfacial interaction: Calcium silicates and polyalkenoates. J. Dent. Res. 2012, 91, 454–459.
  27. Kim J., Nosrat A., Fouad A.: Interfacial characteristics of Biodentine and MTA with dentine in simulated body fluid. J. Dent. 2015, 43, 241–247.
  28. Moinzadeh A., Aznar C. Portoles, Schembri P. Wismayer, Camilleri J.: Bioactivity potential of EndoSequence BC RRM Putty. J. Endod. 2016, 42, 615–621.
  29. Naghavi N., Ghoddusi J., Sadeghnia H., Asadpour E., Asgary S.: Genotoxicity and cytotoxicity of mineral trioxide aggregate and calcium enriched mixture cements on L929 mouse fibroblast cells. Dent. Mat. J. 2014, 33, 64–69.
  30. Willershausen I., Wolf T., Kasaj A., Weyer V., Willershausen B., Marroquin B.: Influence of a bioceramic root end material and mineral trioxide aggregates on fibroblasts and osteoblasts. Arch. Oral Biol. 2013, 58, 1232–1237.
  31. Da T. Fonseca, Da G. Silva, Tanomaru M.-Filho, Sasso E.-Cerri, Guerreiro J.-Tanomaru, Cerri P.: In vivo evaluation of the inflammatory response and IL-6 immunoexpression promoted by Biodentine and MTA Angelus. Int. Endod. J. 2016, 49, 145–153.
  32. Rahimi S., Mokhtari H., Shahi S., Kazemi A., Asgary S., Eghbal M., Mesgariabbasi M., Mohajeri D.: Osseous reaction to implantation of two endodontic cements: mineral trioxide aggregate (MTA) and calcium enriched mixture (CEM). Med. Oral Patol. Oral Cir. Bucal. 2012, 17, 907–911.
  33. Hassanien E., Abu A.-Seida, Hashem A., Khanbash S.: Histologic evaluation of furcation perforation treated with mineral trioxide aggregate and BioAggregate. Asian J. Anim. Sci. 2015, 9, 148–156.
  34. Chen I., Karabucak B., Wang C., Wang H., Koyama E., Kohli M., Nah H., Kim S.: Healing after root-end microsurgery by using mineral trioxide aggregate and a new calcium silicate-based bioceramic material as root-end filling materials in dogs. J. Endod. 2015, 41, 389–399.
  35. Shinbori N., Grama A., Patel Y., Woodmansey K., He J.: Clinical outcome of endodontic microsurgery that uses EndoSequence BC root repair material as the root-end filling material. J. Endod. 2015, 41, 607–612.
  36. Bortoluzzi E., Miu L., Palani C., El-Awady A.R, Hammond B., Pei D., Tian F., Cutler C., Pashley D., Tay F.: Cytotoxicity and osteogenic potential of silicate calcium cements as potential protective materials for pulpal revascularization. Dent. Mater. 2015, 31, 1510–1522.
  37. Saberi E., Karkehabadi H., Mollashahi N.: Cytotoxicity of various endodontic materials on stem cells of human apical papilla. Iran Endod. J. 2016, 11, 17–22.
  38. Jaberiansari Z., Naeri S., Tabatabaei F.: Cytotoxic effects of various mineral trioxide aggregate formulations, calcium-enriched mixture and a new cement on human pulp stem cells. Iran. Endod. J. 2014, 9, 271–276.
  39. Jung J., Woo S., Lee B., Koh J., Nor J., Hwang Y.: Effect of Biodentine and BioAggregate on odontoblastic differentiation via mitogen-activated protein kinase pathway in human dental pulp cells. Int. Endod. J. 2015, 48, 177–184.
  40. Machado J., Johnson J., Paranjpe A.: The effects of EndoSequence Root Repair Material on differentiation of dental pulp cells. J. Endod. 2016, 42, 101–105.
© Wroclaw Medical University