Dental and Medical Problems

Dent. Med. Probl.
Index Copernicus (ICV 2019) – 118.76
MNiSW – 20
CiteScore (2020) – 1.2
Average rejection rate (2020) – 88.71%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2016, vol. 53, nr 1, January-March, p. 125–133

doi: 10.17219/dmp/60236

Publication type: clinical case

Language: English

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Creative Commons BY-NC-ND 3.0 Open Access

SAPHO Syndrome as a Potential Cause of Chronic Mandibular Bone Inflammation and Temporomandibular Joint Dysfunction – Case Report

Zespół SAPHO jako potencjalna przyczyna przewlekłego zapalenia kości żuchwy oraz zaburzeń funkcji stawów skroniowo-żuchwowych – opis przypadku

Aleksandra Kustroń1,A,B,C,D, Paweł Stępień1,A,B,C,F, Hanna Gerber1,E,F

1 Department of Maxillofacial Surgery, Wroclaw Medical University, Wrocław, Poland

Abstract

SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) is a rare disease, with an unknown, probably multifactor etiology, comprising osteoarticular disorders of aseptic inflammatory character, and cutaneous changes of massive acne or palmoplantar pustulosis type. Usually the changes involve the anterior thoracic wall, and sternoclavicular and sacroiliac joints. According to literature reports, the mandible is affected in 10% of cases. The paper presents a case of SAPHO syndrome in an 18-year-old patient, with the involvement of the right body, angle, and branch of the mandible and the right temporomandibular joint. Considering the results of imaging examinations (computed tomography, magnetic resonance, and scintigraphy), as well as laboratory, histopathological and microbiological investigations, the authors discuss the possible diagnostic problems and the differentiation of SAPHO syndrome with other diseases. The article also presents different treatment methods, including temporomandibular joint reconstruction with the use of an alloplastic prosthesis. The aim of the paper is to present SAPHO syndrome as a potential cause of primarily chronic mandibular bone inflammation and stomatognathic system dysfunction.

Key words

SAPHO syndrome, mandibular bone inflammation, hyperostosis, temporomandibular joint inflammation, acne

Słowa kluczowe

zespół SAPHO, zapalenie kości szczęk, hiperostoza, zapalenie stawów skroniowo-żuchwowych, trądzik

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