Dental and Medical Problems

Dent. Med. Probl.
Index Copernicus (ICV 2019) – 118.76
MNiSW – 20
CiteScore (2020) – 1.2
Average rejection rate (2020) – 88.71%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2015, vol. 52, nr 3, July-September, p. 330–335

Publication type: review article

Language: English

Creative Commons BY-NC-ND 3.0 Open Access

Biochemical, Microbiological and Molecular Characteristics of Chronic and Aggressive Periodontitis

Przewlekłe i agresywne zapalenie przyzębia – porównanie w aspekcie mikrobiologicznym, biochemicznym i molekularnym

Jakub Dyba1,A,B,C, Anna Surdacka1,A,E,F, Marcin Lenkowski1,A,B,C,D

1 Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, Poznań, Poland

Abstract

In 1999, a novel classification of periodontal diseases was advocated by International Workshop for a Classification of Periodontal Diseases. It clearly demarcates the nomenclature and diagnostic criteria of periodontal diseases, emphasizing generalized aggressive periodontitis and Generalized chronic periodontitis. Although periodontal disease has been subdivided into two entities, its classification and diagnosis still presents an issue. It is obvious that with the advent of technological advancement a new system ought to be created, enabling clinicians to pinpoint the diagnosis. Research teams are utilizing various forms of assays in order to develop a more lucid understanding on how to differentiate between the two forms of the disease. The aim of our review was to show whether there are any differences and/or similarities between the two forms of periodontitis at the biochemical, microbiological and molecular level. Although future prospects in the field of molecular biology may assist clinicians through the development of a innovative “intrinsic” classification we still have to develop a better understanding of the etiological factors, pathogenesis, genetics and how microorganisms are linked with various types of periodontal disease.

Key words

chronic periodontitis, agressive periodontitis, classification

Słowa kluczowe

przewlekłe zapalenie przyzębia, agresywne zapalenie przyzębia, klasyfikacja

References (40)

  1. Van der Velden U.: Purpose and problems of periodontal disease classification. Periodontol. 2000, 2005, 39, 13–21.
  2. Pihlstrom B.L., Michalowicz B.S., Johnson N.W.: Periodontal diseases. Lancet, 2005, 366, 1809–1820.
  3. American Academy of Periodontology: 1999 International workshop for a classification of periodontal diseases and conditions. In: Caton J.G., Armitage G.C., editors. Illinois: Oak Brook, Ann. Periodontol. 1999, 4, 1–112.
  4. Armitage C., Cullinan P.M.: Comparison of the clinical features of chronic and aggressive periodontitis. Periodontol. 2000, 2010, 53, 12–27.
  5. Cronin A.J., Claffey N., Stassen L.F.: Who is at risk? Periodontal disease risk analysis made accessible for the general dental practitioner. Br. Dent. J. 2008, 205, 131–137.
  6. Mealey B.L., Rethman M.P.: Periodontal disease and diabetes mellitus. Bidirectional relationship. Dent. Today 2003, 22, 107–113.
  7. Mealey B.L., Moritz A.J.: Hormonal influences: effects of diabetes mellitus and endogenous female sex steroid hormones on the periodontium. Periodontol. 2000, 2003, 32, 59–81.
  8. Heikkinen A.M., Pajukanta R., Pitkaniemi J., Broms U., SorsaT., Koskenvuo M., Meurman J.H.: The effect of smoking on periodontal health of 15- to 16-year-old adolescents. J. Periodontol. 2008, 79, 2042–2047.
  9. Highfield J.: Diagnosis and classification of periodontal disease. Aust. Dent. J. 2009, 54, S11–S26.
  10. Deas D.E., Mackey S.A., McDonnell H.T.: Systemic disease and periodontitis: manifestations of neutrophil dysfunction. Periodontol. 2000, 2003, 32, 82–104.
  11. Ryder I.M.: Comparison of neutrophil functions in aggressive and chronic periodontitis. Periodontol. 2000, 2010, 55, 124–137
  12. Ziętek M.: Aktywność granulocytów obojętnochłonnych w pomłodzieńczym zapaleniu przyzębia. Praca habilitacyjna, Wrocław 1990.
  13. Konopka T.: Wpływ leczenia chirurgicznego i farmakologicznego na aktywność neutrofilów w progresywnych zapaleniach przyzębia. Praca doktorska, Wrocław 1993.
  14. Guentsch A., Puklo M., Preshaw P.M., Glockmann E., Pfister W., Potempa J., Eick S.: Neutrophils in chronic and aggressive periodontitis in interaction with Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. J. Periodont. Res. 2009, 44, 368–377.
  15. Kurtiş B., Tüter G., Serdar M., Akdemir P., Uygur C., Firatli E., Bal B.: Gingival crevicular fluid levels of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha in patients with chronic and aggressive periodontitis. J. Periodontol. 2005, 76,1849–1855.
  16. Loos B.G., John R.P., Laine M.L.: Identification of genetic risk factors for periodontitis and possible mechanisms of action. J. Clin. Periodontol. 2005, 32(Suppl. 6), 159–179.
  17. Duarte P.M., da Rocha M., Sampaio E., Mestnik M.J., Feres M., Figueiredo L.C., Bastos M.F., Faveri M.: Serum levels of cytokines in subjects with generalized chronic and aggressive periodontitis before and after nonsurgical periodontal therapy: A pilot Study. J. Periodontol. 2010, 81, 1056–1063.
  18. Olfat G.S.. Noha A.G.: IL-17 and IL-11 GCF Levels in aggressive and chronic periodontitis patients: relation to PCR bacterial detection. Med. Inflammat. 2012, Article ID 174764.
  19. Giannopoulou C., Kamma J.J., Mombelli A.: Effect of inflammation, smoking and stress on gingival crevicular fluid cytokine level. J. Clin. Periodontol. 2003, 30, 145–153.
  20. Rescala B., Rosalem W. Jr., Teles R.P., Fischer R.G., Haffajee A.D., Socransky S.S., Gustafsson A., Figueredo C.M.: Immunologic and microbiologic profiles of chronic and aggressive periodontitis subjects. J. Periodontol. 2010, 81, 1308–1316.
  21. Suzuki M., Ishihara Y., Kamiya Y., Koide M., Fuma D., Fujita S., Matsumura Y., Suga T., Kamei H., Noguchi T.: Soluble interleukin-1 receptor type II levels in gingival crevicular fluid in aggressive and chronic periodontitis. J. Periodontol. 2008, 79, 495–500.
  22. Artese L., Piattelli A., Aparecida de Gouveia Cardoso L., S.Ferrari D., Onuma T., Piccirilli M., Faveri M., Perrotti V., Simon M., Awad Shibli J.: Immunoexpression of angiogenesis, nitric oxide synthase, and proliferation markers in gingival samples of patients with aggressive and chronic periodontitis. J. Periodontol. 2010, 81, 718–726.
  23. Byun J.H., Park B.W., Kim J.R., Lee J.H.: Expression of vascular endothelial growth factor and its receptors after mandibular distraction osteogenesis. Int. J. Oral Maxillofac. Surg. 2007, 36, 338–344.
  24. Unlu F., Guneri P.G., Hekimgli M., Yesilbek B., Boyaciaglu H.: Expression of vascular endothelial growth factor in human periodontal tissues: Comparison of healthy and diabetic patients. J. Periodontol. 2003, 74, 181–187.
  25. Albandar J.M.: Periodontal diseases in North America. Periodontol. 2000, 2002, 29, 31–69.
  26. Axelsson P., Albandar J.M., Rams T.E.: Prevention and control of periodontal diseases in developing and industrialized nations. Periodontol. 2000, 2002, 29, 235–246.
  27. Gjermo P., Rosing C.K., Susin C., Oppermann R.: Periodontal diseases in Central and South America. Periodontol. 2000, 2002, 29, 70–78.
  28. Botero J.E., Contreras A., Lafaurie G., Jaramillo A., Betancourt M., Arce R.M.: Occurrence of periodontopathic and superinfecting bacteria in chronic and aggressive periodontitis subjects in a Colombian population. J. Periodontol. 2007, 78, 696–704.
  29. Habashneh R.A., Karasneh J.A.: Predominant microflora in chronic and generalized aggressive periodontitis in a Jordanian population. Dent. 2006, 193. DOI:10.4172/2161-1122.1000193
  30. Dogan B., Antinheimo J., Cetiner D.: Subgingival microflora in Turkish patients with periodontitis. J. Periodontol. 2003, 74, 803–814.
  31. Darby I.B., Hodge P.J., Riggio M.P., Kinane D.F.: Clinical and microbiological effect of scaling and root planning in smoker and non-smoker chronic and aggressive periodontitis patients. J. Clin. Periodontol. 2005, 32, 200–206.
  32. Ximenez-Fyvie L.A., Almaguer-Flores A., Jacobo-Soto V., Lara-Cordoba M., Moreno-Borjas J.Y., AlcantaraMaruri E.: Subgingival microbiota of periodontally untreated Mexican subjects with generalized aggressive periodontitis. J. Clin. Periodontol. 2006, 33, 869–877.
  33. Kebschull M., Guarnieri P., Demmer R.T., Boulesteix A.L., Pavlidis P., Papapanou P.N.: Molecular differences between chronic and aggressive periodontitis. J. Dent. Res. 2013, 92, 1081–1086.
  34. Brett P.M., Zygogianni P., Griffiths G.S., Tomaz M., Parkar M., D’Aiuto F., Tonetti M.: Functional gene polymorphisms in aggressive and chronic periodontitis. J. Dent. Res. 2005, 84, 1149–1153.
  35. Gonzales J.R., Michel J., Diete A., Herrmann J.M., Bödeker R.H., Meyle J.: Analysis of genetic polymorphisms at the interleukin-10 loci in aggressive and chronic periodontitis. J. Clin. Periodontol. 2002, 29, 816–822.
  36. Schulz S., Machulla H.K.G., Altermann W., Klapproth J., Zimmermann U., Glaser C., Kluttig A., Stein J., Schaller H-G., Reichert S.: Genetic markers of tumor necrosis factor a in aggressive and chronic periodontitis. J. Clin. Periodontol. 2008, 35, 493–500.
  37. Loos B.G., Leppers-van de Straat F.G., van de Winkel J.G., van der Velden U.: Fc-gamma receptor polymorphisms in relation to periodontitis. J. Clin. Periodontol. 2003, 30, 595–602.
  38. Yamamoto K., Kobayashi T., Grossi S., Ho A.W., Genco R.J., Yoshie H., De Nardin E.: Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians. J. Periodontol. 2004, 75, 517–522.
  39. Stein J.M., Machulla H.K., Smeets R., Lampert F., Reichert S.: Human leukocyte antigen polymorphism in chronic and aggressive periodontitis among Caucasians: a meta-analysis. J. Clin. Periodontol. 2008, 35, 183–192.
  40. The biochemistry and cell biology of antigen processing and presentation. Ann. Rev. Immunol. 1993, 11, 403-450.