Dental and Medical Problems

Dent Med Probl
Index Copernicus (ICV 2020) – 128.41
MEiN – 70 pts
CiteScore (2021) – 2.0
JCI – 0.5
Average rejection rate (2021) – 81.35%
ISSN 1644-387X (print)
ISSN 2300-9020 (online)
Periodicity – quarterly

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Dental and Medical Problems

2015, vol. 52, nr 3, July-September, p. 330–335

Publication type: review article

Language: English

Creative Commons BY-NC-ND 3.0 Open Access

Biochemical, Microbiological and Molecular Characteristics of Chronic and Aggressive Periodontitis

Przewlekłe i agresywne zapalenie przyzębia – porównanie w aspekcie mikrobiologicznym, biochemicznym i molekularnym

Jakub Dyba1,A,B,C, Anna Surdacka1,A,E,F, Marcin Lenkowski1,A,B,C,D

1 Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, Poznań, Poland


In 1999, a novel classification of periodontal diseases was advocated by International Workshop for a Classification of Periodontal Diseases. It clearly demarcates the nomenclature and diagnostic criteria of periodontal diseases, emphasizing generalized aggressive periodontitis and Generalized chronic periodontitis. Although periodontal disease has been subdivided into two entities, its classification and diagnosis still presents an issue. It is obvious that with the advent of technological advancement a new system ought to be created, enabling clinicians to pinpoint the diagnosis. Research teams are utilizing various forms of assays in order to develop a more lucid understanding on how to differentiate between the two forms of the disease. The aim of our review was to show whether there are any differences and/or similarities between the two forms of periodontitis at the biochemical, microbiological and molecular level. Although future prospects in the field of molecular biology may assist clinicians through the development of a innovative “intrinsic” classification we still have to develop a better understanding of the etiological factors, pathogenesis, genetics and how microorganisms are linked with various types of periodontal disease.

Key words

chronic periodontitis, agressive periodontitis, classification

Słowa kluczowe

przewlekłe zapalenie przyzębia, agresywne zapalenie przyzębia, klasyfikacja

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