Dental and Medical Problems

Dent Med Probl
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ISSN 1644-387X (print)
ISSN 2300-9020 (online)
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Dental and Medical Problems

2012, vol. 49, nr 2, April-June, p. 293–298

Publication type: review

Language: English

License: Creative Commons Attribution 3.0 Unported (CC BY 3.0)

Tooth Agenesis – a Review of Literature and Own Case Studies

Agenezja zębów w piśmiennictwie i materiale własnym

Maria Mielnik-Błaszczak1,A,B,D,E,F, Anna Piątkowska1,A,B,D,E,F, Anna Machowska2,A,B,D,E,F, Beata Bukowska3,A,B,D,E,F

1 Chair and Department of Paediatric Dentistry University of Medicine in Lublin, Poland

2 Dental Practice Medicare, Mińsk Mazowiecki, Poland

3 Dental Clinical Centre, Lublin, Poland

Abstract

Tooth agenesis is a congenital absence of teeth. It is the most commonly registered developmental anomaly of human dentition. This pathology may affect both the primary and permanent dentition. It occurs separately or in association with another congenital syndromes. This study describes the epidmiology, aetiology, classification and treatment methods of agenesis, based on a review of literature, as well as it presents 3 own cases of this anomaly. Tooth agenesis creates functional and aesthetic problems therefore patients require complex treatment.

Streszczenie

Agenezja zębów jest wadą rozwojową polegającą na braku zawiązków zębów. Należy do najczęstszych wad rozwojowych uzębienia. Dotyczy zarówno zębów mlecznych, jak i stałych. Może występować jako wada izolowana, bądź towarzyszyć różnym zespołom chorobowym. W pracy przedstawiono na podstawie piśmiennictwa epidemiologię, etiologię, klasyfikację i metody leczenia braku zawiązków zębów oraz 3 przypadki hipodoncji pochodzące z materiałów własnych. Pacjenci z agenezją mają wiele problemów funkcjonalnych oraz estetycznych, dlatego powinni być objęci leczeniem kompleksowym.

Key words

tooth agenesis, development disorder

Słowa kluczowe

agenezja zębów, zaburzenia rozwojowe

References (30)

  1. Biedziak B.: Aetiology and occurrence of tooth agenesis – review of the literature. Dent. Med. Probl. 2004, 41, 531–535 [in Polish].
  2. Jędryszek A., Kmiecik M., Paszkiewicz A.: Review of modern knowledge on hypodontia. Dent. Med. Probl. 2009, 46, 118–125 [in Polish].
  3. Proffit W.R.: Etiologia zagadnień ortodontycznych. Ortodoncja współczesna. Wydawnictwo Czelej, Lublin 2001, 109–139.
  4. Permbeton T.J., Gee J., Patel P.I.: Gene discovery for dental anomalies. A primeer for the dental professional. J. Am. Dent. Assoc. 2006, 137, 743–752.
  5. Kusiak A., Kochańska B., Bukowska M., Żółtowska A.: Hypodontia in maxillary permanent dentition – case report. Czas. Stomatol. 2008, 61, 348–352 [in Polish].
  6. Mielnik-Błaszczak M.: Changes in the masticatory organ in ectodermal dysplasia – a case report. Przegl. Stomatol. Wieku Rozw. 2001, 35/36, 51–54 [in Polish].
  7. Biedziak B.: Incidence of malocclusion in patients with oligodontia. Dent. Med. Probl. 2004, 41, 483–488 [in Polish].
  8. Ohno K., Ohmori I.: Anodontia with hypohydrotic ectodermal dysplasia in young female: a case report. Pediatr. Dent. 2000, 22, 49–52.
  9. Marinelli A., Giuntini V., Franchi L., Tollaro I., Baccetti T., Defraia E.: Dental anomalies in the primary dentition and their repetition in the permanent dentition: a diagnostic performance study. Odontology 2012, 100, 1, 22–27.
  10. Swinnen S., Bailleul-Forestier I., Arte S., Nieminen P., Devriendt K., Carels C.: Investigating the etiology of multiple tooth agenesis in three sisters with severe oligodontia. Orthod. Craniofac. Res. 2008, 11, 24–31.
  11. Militi D., Militi A., Cutrupi M.C., Portelli M., Rigoli L., Matarese G., Salpietro D.C.: Genetic basis of non syndromic hypodontia: a DNA investigation performed on three couples of monozyotic twins about PAX9 mutation. Eur. J. Paediatr. Dent. 2011, 12, 21–24.
  12. Bergendal B., Klar J., Stecksen-Blicks C., Norderyd J., Dahl N.: Isolated oligodontia assosiated with mutations in EDARADD, AXIN2, MSX1 and PAX9 genes. Am. J. Med. Gen. A. 2011, 155 (7), 1616–1622.
  13. Vieira A.R., Meira R., Modesto A., Murray J.C.: MSX1, PAX9 and TGFA contribute to tooth agenesis in human. J. Dent. Res. 2004, 83, 723–727.
  14. Pawłowska E., Szczepańska J., Szydłowska B., Lubowiedzka B.: Diagnosis of oligodontia based upon explorative cluster analysis. Czas. Stomatol. 2007, 60, 641–649 [in Polish].
  15. Vastardis H.: The genetics of human tooth agenesis. New discoveries for understanding dental anomalies. Am. J. Orthod. Dentofac. Orthop. 2000, 117, 650–656.
  16. Lagena F., Lombardi C.C., Franchi L., Cozza P.: Tooth agenesis: dento-skeletal characteristics in subjects with orthodontic treatment need. Eur. J. Paediatr. Dent. 2011, 12, 17–20.
  17. Kasperski J., Rosak P., Iwanecka-Zduńczyk M.: Prosthetic treatment of the patient with hipodontia. A case report. Protet. Stomatol. 2006, 56, 295–299 [in Polish].
  18. Da-Woon Ch., Mong-Sook V., Sang-Won P., Hyun-Pil L., Hong-So Y.: Oral rehabilitation for a patient with oligodontia and maxillary hypoplasia. J. Adv. Prosthodont. 2009, 1, 6–9.
  19. Jepson N.J., Nohl F.S., Carter N.E., Gillgrass T.J., Meechan J.G., Hobson R.S., Nunn J.H.: The interdisciplinary management of hypodontia: restorative dentistry. Br. Dent. J. 2003, 194, 299–304.
  20. Nunn J.H., Carter N.E., Gillgrass T.J., Hobson R.S., Jepson N.J., Meechan J.G., Nohl F.S.: The interdisciplinary management of hypodontia, Part 1: background and role of paediatric dentistry. Br. Dent. J. 2003, 194, 245–256.
  21. Jepson N.J., Nohl F.S, Carter N.E., Gillgrass T.J., Meechan J.G., Hobson R.S., Jh Nunn J.H.: The interdisciplinary management of hypodontia, Part 2: restorative dentistry. Br. Dent. J. 2003, 194, 299–304.
  22. Li D., Liu Y., Ma W., Song Y.: Review of ectodermal dysplasia: case report on treatment planning and surgical management of oligodontia with implant restorations. Implant Dent. 2011, 20, 328–330.
  23. Pannu P.K., Kaur A., Simratvir M., Sujlana A.: Agenesis of permanent mandibular anterior teeth: a case report. J. Dent. Child (Chic). 2011, 78, 76–80.
  24. Valle A.L., Lorenzoni F.C., Martins L.M., Valle C.V., Henriques J.F., Almeida A.L., Pegoraro L.F.: A multidisciplinary approach for the management of hypodontia: case report. J. Appl. Oral. Sci. 2011, 19, 544–548.
  25. Bural C., Oztas E., Ozturk S., Bayraktar G.: Multidisciplinary treatment of non-syndromic oligodontia. Eur. J. Dent. 2012, 6, 218–226.
  26. Kaczmarek U.: Autotransplantation of teeth. Dent. Med. Probl. 2006, 43, 277–281 [in Polish].
  27. Park J.H., Kim D.A., Tai K.: Congenitlly missing maxillary lateral incisors: treatment. Dent. Today 2011, 30, 81–82, 84–86.
  28. Krasner P., Verlander P.: Stem cells in dentistry and medicine: the dentist’s role. Dent. Today 2011, 30, 128, 130–134.
  29. Liu H., Cao T.: Dental application potential of mesenchymal stromal cells and embryonic stem cells. Chin. J. Dent. Res. 2010, 13, 95–103.
  30. Ikededa E., Tsui T.: Growing bioengineered teeth from single cells: potential for dental regenerative medicine. Expert. Opin. Biol. Ther. 2008, 8, 735–744.
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